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GROWTH DIFFERENTIATION FACTOR 1
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DeCS
Descriptor
English
:
Growth Differentiation Factor 1
Descriptor
Spanish
:
Factor 1 de Diferenciación de Crecimiento
Descriptor
Portuguese
:
Fator 1 de Diferenciação de Crescimento
Synonyms
English
:
GDF-1
Tree Number:
D12.644.276.954.300.100
D12.644.276.954.550.100
D12.776.467.942.300.100
D12.776.467.942.550.100
D23.529.942.300.100
D23.529.942.550.100
Definition
English
:
A
growth
differentiation factor that plays a role in the genesis of left-right asymmetry during
vertebrate
development. Evidence for this role is seen in MICE where loss of
growth differentiation factor 1
function results in right-left
isomerism
of visceral organs. In
HUMANS
heterozygous loss of
growth differentiation factor 1
function has been associated with CONGENITAL HEART DEFECTS and
TRANSPOSITION OF GREAT VESSELS.
History Note
English
:
2009(2005)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53139
Unique Identifier:
D055452
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS